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Heritability of Fatty Liver as Measured by MRI: A Cross Sectional Study of Twins and Family Members |
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| SUBJECTS NEEDED: Twins above the age of 18 years. 240 twins will be used for this study. |
| LOCATION: San Diego, CA |
| PURPOSE OF STUDY: The purpose of this study is
to evaluate interaction between genes and the amount of fat in the liver by
studying twins. This study will also help understand how genetics relate to
common diseases such as high blood pressure, cholesterol, and diabetes and
their association with fatty liver. |
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INVESTIGATOR:
Rohit Loomba, Archana Bhatt, Thu Nguyen
200 West Arbor Drive
MC 8413
San Diego, CA 92103-8413
Telephone: 619-471-3915
Fax: (619) 543-2160
E-mail:
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| INITIATION DATE: August 23, 2011 |
COMPLETION DATE: August 23, 2016 |
| METHOD OF INVESTIGATION:
For each subject, the total study visit will take 2-2.5 hours. You will
be asked to come in a fasting state and we will draw blood. An interview will
also be conducted, you will get a physical exam and have your blood pressure,
temperature, pulse, height and weight checked. We will ask about your alcohol
consumption and medication use. You will also have an ultrasound and MRI and
provide a urine sample.
You
will be compensated for participation in the study ($100). We will inform
you if you have fatty liver and suggest any need for clinical follow up. We
will also provide specific dietary recommendations should you have fatty liver
to reduce your risk for heart and liver disease. |
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