National Institutes of Health Twin Study
SUBJECTS NEEDED: Healthy identical and same-sex fraternal twins, ages 4-25
LOCATION: No restriction, anywhere in the United States
PURPOSE OF STUDY: To study brain growth and the relationship between brain structure and function in healthy children and adolescents.

INVESTIGATOR: Jay Giedd, M.D.
National Institutes of Mental Health
Bldg 10, Room 4C110
10 Center, MSC 1397
Bethesda, MD 20892-1367
Phone: (301) 435-4515
Contact:
Alexis Hedrick, Research Coordinator
Email:  This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
FAX: (301) 480-8898

INITIATION DATE: Summer 1998 COMPLETION DATE: Open-ended
METHOD OF INVESTIGATION: Potential participants will be contacted by telephone and then mailed questionnaires to be completed by parents and teachers. Twins who meet the criteria will be invited to the NIH for a magnetic resonance imaging (MRI) scan. MRI produces detailed images of the brain without the use of needles or "x-rays", i.e., no radioactivity. In addition to the MRI, we do a cheek swab to determine twin zygosity, conduct interviews, and do some cognitive testing. All services are free of charge. Transportation to NIH will be reimbursed and accommodations will be provided for a 2- to 3-night stay. Depending on degree of participation in the study, families may be given an "inconvenience fee" of up to $160 per twin. In addition, twins will receive pictures of their brains to bring home.